South Africa skipper Temba Bavuma will also miss the second Test against Bangladesh that starts at the Zahur Ahmed Chowdhury Stadium in Chattogram from October 29.
An elbow muscle strain prevented Bavuma from playing the first Test in Dhaka which South Africa won by seven wickets.
Though Bavuma has made significant progress in his rehabilitation, he will not be match-fit before the second Test, according to a press release by Cricket South Africa.
Aiden Markram will continue to lead the South Africa in Bavuma鈥檚 absence.
Meanwhile Bangladesh made one change to the squad from the first Test with pacer Khaled Ahmed replacing Taskin Ahmed.
Following their win against Bangladesh in the first Test, South Africa climbed to fourth place on the table with a points percentage of 47.62.
Meanwhile, Bangladesh currently sits in seventh place with a points percentage of 30.56.
Squad: Aiden Markram (captain), David Bedingham, Matthew Breetzke, Dewald Brevis, Tony de Zorzi, Keshav Maharaj, Wiaan Mulder, Senuran Muthusamy, Lungi Ngidi, Dane Paterson, Dane Piedt, Kagiso Rabada, Tristan Stubbs, Ryan Rickelton, and Kyle Verreynne.
